There is also a strong link between HSV2 and HIV, where people infected with HSV2 are three times more likely to contract HIV. The recurrent nature of genital herpes can lead to stigma and psychological distress, impacting the quality of life and sexual relationships. Furthermore, research shows a majority of individuals develop a resistance to treatment. Although antiviral medications are available in the market to suppress the virus, there is no cure. Herpes is a lifelong infection that often goes undetected. Over half a billion of the global population lives with a genital herpes infection (caused by HSV2), while several billion lives with an oral herpes infection (caused by HSV1). Herpes: the silent pandemic affecting 90% of the global population UB-621 is a first-in-class anti-gD mAb (UB-621) with demonstrated strong viral suppression of transmission and recurrence of HSV1 and HSV2, developed over ten years of research collaboration between the University of Washington, the National Institute for Allergy and Infectious Diseases, University of Duisburg Essen, Germany, and Dartmouth College. Shugene, Lin, President of United BioPharma. With Cheng Kung University and the Shanghai Public Health Clinical Centre’s support, we hope to demonstrate further the capability of UB-621 as we move to phase two trials,” added Dr. “We know UB-621 can neutralize over 40 HSV isolates from Asia, the United States and Germany. “Data from our initial trials suggest that UB-621 is not only a best-in-class treatment but a potential game-changer for billions of patients suffering from herpes worldwide Testing on clinical isolates will help confirm whether UB-621 can work well against herpes strains, especially those that have already shown to be resistant to currently marketed drugs”, said Dr. The latest additions to the partnership will work with existing partners to test the neutralizing activity of UB-621 to the HSV clinical isolates in mainland China and Taiwan. Bernard Heymann, Ph.D., NIAMS Laboratory of Structural Biology Research The herpes simplex virus-1, which causes most cases of ocular herpes. Together with United BioPharma, the two institutions will test the effectiveness of UB-621, a best-in-class long-acting treatment for genital herpes caused by simplex viruses 1 and 2 (HSV 1 and HSV2) in preparation for phase II trials in the United States and China.
By NewsDesk BioPharma announced this week that Shanghai Public Health Clinical Centre and Cheng Kung University’s Department of Microbiology and Immunology have joined United BioPharma’s fight against the global herpes endemic.
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